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中文人类
LTA - Lymphotoxin Alpha
Alias:
LT
TNFB
TNFSF1
TNLG1E
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肿瘤坏死因子家族成员，编码的蛋白质是一种由淋巴细胞产生的细胞因子。该蛋白质具有高度诱导性、分泌性，并与淋巴细胞毒素-β形成异源三聚体，将淋巴细胞毒素-α锚定在细胞表面上。该蛋白质还介导各种炎症、免疫刺激和抗病毒反应，参与发育过程中次级淋巴器官的形成，并在凋亡中发挥作用。该基因的遗传变异与麻风病4型、心肌梗死、非霍奇金淋巴瘤和银屑病关节炎的易感性有关。已观察到该基因的可变剪接转录变异体。[RefSeq，2012年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
LTA Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
