人类

LTA4H - Leukotriene A4 Hydrolase

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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码的蛋白质是一种同时具有水解酶和氨基肽酶活性的酶。水解酶活性用于白细胞三烯B4生物合成的最后步骤,这是一种前炎症介质。氨基肽酶活性已被证明可以降解精氨酸-甘氨酸-精氨酸(PGP),这是一种嗜中性粒细胞的化学吸引剂和慢性阻塞性肺疾病(COPD)的生物标志物。已经发现这个基因有几个转录变异体,编码不同的异构体。[由RefSeq,2015年9月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
9
19
42768 bp
69.28
23
--
11
32

LTA4H Genetics information (-)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
Tutorials
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