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中文人类
LRP6 - LDL Receptor Related Protein 6
Alias:
ADCAD2
STHAG7
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这个基因编码低密度脂蛋白(LDL)受体基因家族的成员。LDL受体是跨膜细胞表面蛋白质，参与脂蛋白和蛋白质配体的受体介导的内吞作用。这个基因编码的蛋白质作为Wnt的受体或辅受体与Frizzled共同作用，从而传递典型的Wnt/beta-catenin信号级联。通过与Wnt/beta-catenin信号级联相互作用，这个基因在细胞分化、增殖和迁移的调控以及许多癌症类型的发展中发挥作用。这个蛋白质经历γ-分泌酶依赖的RIP-(调控膜内蛋白水解)加工，但切割位点的精确位置尚未确定。[RefSeq，2009年12月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
LRP6 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
