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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
LPA - Lipoprotein(a)
Alias:
LP
AK38
APOA
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Description
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码的蛋白质是一种丝氨酸蛋白酶,能抑制组织型纤溶酶原激活物I的活性。编码的蛋白质是脂蛋白(a)的主要组成部分,并通过蛋白水解作用被切割成片段,这些片段附着在动脉粥样硬化病变上并促进血栓形成。这个蛋白质的升高血浆水平与动脉粥样硬化有关。根据个体差异,编码的蛋白质含有2-43个kringle型结构域拷贝。这里代表的等位基因含有15个kringle型重复序列,与参考基因组序列中发现的相应等位基因相对应。[由RefSeq,2009年12月提供]
Related ID:
NCBI:4018
ENSEMBL:ENSG00000198670
HGNC:6667
UNIPROT:P08519
OMIM:152200
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
4018
1
39
132794 bp
226.55
102
1
4
9
LPA Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
No data available
Transcripts & Proteins
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
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Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available
Related Drugs
Name
CAS Number
Status
Phase
Link
No data available
References Literature
Title
PMID
Journal
Year
IF
No Data Found!
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