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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
PAIP2B - Poly(A) Binding Protein Interacting Protein 2B
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
除了组蛋白之外,大多数mRNA含有3'端聚(A)尾。聚(A)结合蛋白(PABP;参见MIM 604679)通过与翻译起始因子EIF4G1(MIM 600495)和聚(A)尾相互作用,通过将mRNA循环化来增强翻译。各种PABP结合蛋白调节PABP活性,包括PAIP1(MIM 605184),一种翻译刺激剂,以及PAIP2A(MIM 605604)和PAIP2B,翻译抑制剂(Derry等,2006[PubMed 17381337])。[由OMIM于2008年3月提供]
Related ID:
NCBI:400961
ENSEMBL:ENSG00000124374
HGNC:29200
UNIPROT:Q9ULR5
OMIM:611018
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
400961
4
4
44366 bp
14.24
4
--
4
3
PAIP2B Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
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Transcripts & Proteins
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Transcript
Length(nt)
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CDS(bp)
Protein
Length(aa)
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* This data comes from NCBI.
Gene Expression
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References Literature
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