人类

PAIP2B - Poly(A) Binding Protein Interacting Protein 2B

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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
除了组蛋白之外,大多数mRNA含有3'端聚(A)尾。聚(A)结合蛋白(PABP;参见MIM 604679)通过与翻译起始因子EIF4G1(MIM 600495)和聚(A)尾相互作用,通过将mRNA循环化来增强翻译。各种PABP结合蛋白调节PABP活性,包括PAIP1(MIM 605184),一种翻译刺激剂,以及PAIP2A(MIM 605604)和PAIP2B,翻译抑制剂(Derry等,2006[PubMed 17381337])。[由OMIM于2008年3月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
4
4
44366 bp
14.24
4
--
4
3

PAIP2B Genetics information (-)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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