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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Flrt2 - fibronectin leucine rich transmembrane protein 2
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个句子很长,我将为您提取关键信息并翻译成中文。 这个分子(FLRT2)具有化学趋化活性(chemorepellent activity)和成纤维细胞生长因子受体结合活性(fibroblast growth factor receptor binding activity)。它参与基底膜组织(basement membrane organization),心脏形态发生(heart morphogenesis)中的细胞粘附(cell adhesion)以及成纤维细胞生长因子受体信号通路(fibroblast growth factor receptor signaling pathway)。它位于轴突引导(axon guidance)的上游或内部,正向调节突触组装(positive regulation of synapse assembly)以及调控神经元迁移(regulation of neuron migration)。它位于细胞间连接(cell-cell junction)和细胞外空间(extracellular space)。它是质膜的整合成分(integral component of plasma membrane),与粘附斑(focal adhesion)共定位。它在包括消化系统上皮(alimentary system epithelium)、鳃弓(branchial arch)、中枢神经系统(central nervous system)、胚胎间充质(embryo mesenchyme)和感觉器官(sensory organ)在内的几个结构中表达。它与人类的FLRT2(fibronectin leucine rich transmembrane protein 2)具有同源性。
Related ID:
NCBI:399558
ENSEMBL:ENSMUSG00000047414
UNIPROT:Q8BLU0
Basic Information
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Transcripts
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Length
MW (kDa)
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399558
5
2
93210 bp
73.95
9
13
Flrt2 Genetics information (+)
GRCm39
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* This data comes from NCBI.
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