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中文人类
LIMS1 - LIM Zinc Finger Domain Containing 1
Alias:
PINCH
PINCH1
PINCH-1
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这个基因编码的蛋白质是一种含有五个LIM结构域或两个锌指的衔接蛋白。该蛋白质可能通过其LIM结构域与整合素连接激酶的相互作用参与整合素信号传导，整合素连接激酶位于粘着斑中。人们认为它还可以作为桥梁将整合素连接激酶与NCK衔接蛋白2连接起来，后者参与生长因子受体激酶信号传导途径。其定位在扩散细胞的周围也提示这个蛋白质可能在整合素介导的细胞粘附或扩散中发挥作用。已经发现这个基因的几个转录变异体，编码不同的异构体。[由RefSeq，2010年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
LIMS1 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
