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中文人类
LIG1 - DNA Ligase 1
Alias:
LIGI
IMD96
hLig1
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这个基因编码一个ATP依赖的DNA连接酶蛋白家族的成员。编码的蛋白质在DNA复制、重组和碱基切除修复过程中发挥作用。这个基因中的突变导致DNA连接酶I缺乏，导致免疫缺陷和对DNA损伤剂的敏感性增加。这个基因的破坏可能与多种癌症有关。可变剪接导致多个转录变异体。[由RefSeq，2014年1月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
LIG1 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
