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中文人类
ARHGDIB - Rho GDP Dissociation Inhibitor Beta
Alias:
D4
GDIA2
GDID4
LYGDI
Ly-GDI
RAP1GN1
RhoGDI2
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Rho蛋白家族（或ARH）成员（参见MIM 165390）和其他Ras相关的小GTP结合蛋白（参见MIM 179520）参与多种细胞事件，包括细胞信号传导、增殖、细胞骨架组织和分泌。GTP结合蛋白只有在GTP结合状态下才是活跃的。至少有3类蛋白质紧密调节GTP结合和GDP结合状态之间的循环：GTP酶激活蛋白（GAPs）、鸟苷核苷酸释放因子（GRFs）和GDP解离抑制剂（GDIs）。GDIs，包括ARHGDIB，降低Ras样GTPases从GDP解离的速度（由Scherle等人于1993年总结[PubMed 8356058]）。[由OMIM于2010年12月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
ARHGDIB Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
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Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
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Tile View
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Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
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Abundance
Alphabetical
Interactions
Acting
Regulation
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Name
MGI
Strain of Origin
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References Literature
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