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中文人类
LGALS3 - Galectin 3
Alias:
L31
GAL3
MAC2
CBP35
GALBP
GALIG
LGALS2
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这个基因编码半乳凝素家族的一员，这个家族成员具有亲和力的β-半乳糖苷。编码的蛋白质的特征是N-末端富含脯氨酸的串联重复结构和单个C-末端的糖识别结构域。这个蛋白可以通过N-末端结构域自我结合，从而使其能够结合多价糖配体。这个蛋白定位在细胞外基质、细胞质和细胞核中。这个蛋白在包括凋亡、先天免疫、细胞粘附和T细胞调节在内的多种细胞功能中发挥作用。这个蛋白展示了抗细菌和抗真菌的抗菌活性。交替剪接导致多个转录变异体。[RefSeq,2014年10月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
LGALS3 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
