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中文人类
LCP2 - Lymphocyte Cytosolic Protein 2
Alias:
IMD81
SLP76
SLP-76
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这个基因编码一个适配器蛋白，作为T细胞抗原受体（TCR）激活的蛋白质酪氨酸激酶途径的底物。编码的蛋白质与生长因子受体结合蛋白2结合，被认为在TCR介导的细胞内信号传导中起作用。小鼠中类似的蛋白质在正常T细胞发育和激活中起作用。缺乏这个基因的小鼠表现出皮下和腹膜内胎儿出血、血小板功能异常和生存能力受损。[RefSeq, Nov 2016提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
LCP2 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
