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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
LCN2 - Lipocalin 2
Alias:
p25
24p3
MSFI
NGAL
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码一个属于脂质运载蛋白家族的蛋白质。这个家族的成员可以运输一些小疏水分子,如脂质、类固醇激素和类胡萝卜素。这个基因编码的蛋白质是一种中性粒细胞明胶酶相关脂质运载蛋白,通过限制含有铁的侧群素(siderophores)的细菌生长,在先天免疫中发挥作用。这个蛋白质在血液和尿液中的存在是急性肾损伤的早期生物标志物。这个蛋白质被认为参与多种细胞过程,包括维持皮肤稳态,以及抑制侵袭性和转移。缺乏这个基因的小鼠比野生型小鼠更容易感染细菌。[RefSeq, 2015年9月提供]
Related ID:
NCBI:3934
ENSEMBL:ENSG00000148346
HGNC:6526
UNIPROT:P80188
OMIM:600181
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
3934
2
7
4001 bp
22.59
17
--
13
24
LCN2 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
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Transcripts & Proteins
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Transcript
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* This data comes from NCBI.
Gene Expression
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Name
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