Home
Toolbox
Resource
Workflow
Tutorials
Citations
Downloads
Mutation Al-Predictor Flow
Gene-to-Mutation Flow
News & Insights
Genetic Encyclopedia
Frontiers
Industry Insights
Case Studies
About Us
About the Site
Contact Us
Private Policy
User Agreement
COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
Log In
|
Sign Up
中文
人类
LCK - LCK Proto-oncogene, Src Family Tyrosine Kinase
Alias:
LSK
YT16
IMD22
p56lck
pp58lck
Create a favorites folder
Cancel
Confirm
Add To Favorites
Select a favorites
Description
New favorites >>
Cancel
Confirm
Favorite
Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因是Src家族酪氨酸激酶(PTKs)的成员。编码的蛋白质是选择和成熟发育中的T细胞的关键信号分子。它包含N端的甲基化和棕榈酰化位点,一个PTK域,以及SH2和SH3域,这些域参与介导与磷酸酪氨酸和富含脯氨酸的模式的蛋白质-蛋白质相互作用。该蛋白质定位在细胞膜和细胞周质中心体小窝,并结合细胞表面受体,包括CD4和CD8,以及其他信号分子。已经描述了编码不同亚型的多个可变剪接变体。[由RefSeq提供,2016年8月]
Related ID:
NCBI:3932
ENSEMBL:ENSG00000182866
HGNC:6524
UNIPROT:P06239
OMIM:153390
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
3932
8
13
34901 bp
58.00
213
1
14
56
LCK Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
No data available
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Reset
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available
Related Drugs
Name
CAS Number
Status
Phase
Link
No data available
References Literature
Title
PMID
Journal
Year
IF
No Data Found!
Wechat
Mutation Direct
Sequence
Comparison
Al agent
Tutorials
Back to top