人类

LBP - Lipopolysaccharide Binding Protein

Alias:
BPIFD2
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码的蛋白质参与对革兰阴性细菌感染的的急性期免疫应答。革兰阴性细菌在其外壁上有糖脂质,即脂多糖(LPS)。与杀菌通透性增加蛋白(BPI)一起,编码的蛋白质结合LPS并与CD14受体相互作用,可能在中枢调节LPS依赖的单核细胞反应中发挥作用。研究表明,编码的蛋白质对于LPS的快速急性期反应是必要的,但对于从循环中清除LPS不是必要的。这个蛋白质是结构上和功能上相关的蛋白质家族的一部分,包括BPI、血浆胆固醇酯转移蛋白(CETP)和磷脂转移蛋白(PLTP)。[RefSeq,2012年4月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
1
15
30532 bp
53.38
29
--
7
12

LBP Genetics information (+)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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