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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
LBP - Lipopolysaccharide Binding Protein
Alias:
BPIFD2
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Description
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码的蛋白质参与对革兰阴性细菌感染的的急性期免疫应答。革兰阴性细菌在其外壁上有糖脂质,即脂多糖(LPS)。与杀菌通透性增加蛋白(BPI)一起,编码的蛋白质结合LPS并与CD14受体相互作用,可能在中枢调节LPS依赖的单核细胞反应中发挥作用。研究表明,编码的蛋白质对于LPS的快速急性期反应是必要的,但对于从循环中清除LPS不是必要的。这个蛋白质是结构上和功能上相关的蛋白质家族的一部分,包括BPI、血浆胆固醇酯转移蛋白(CETP)和磷脂转移蛋白(PLTP)。[RefSeq,2012年4月提供]
Related ID:
NCBI:3929
ENSEMBL:ENSG00000129988
HGNC:6517
UNIPROT:P18428
OMIM:151990
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
3929
1
15
30532 bp
53.38
29
--
7
12
LBP Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
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No data available
Transcripts & Proteins
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#
Transcript
Length(nt)
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CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
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Cell-specific RNA expression
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Type
Name
MGI
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No data available
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CAS Number
Status
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Link
No data available
References Literature
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IF
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