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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
RHOG - Ras Homolog Family Member G
Alias:
ARHG
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码Rho家族的小GTP酶成员,它们在活性GTP结合和非活性GDP结合状态之间循环,作为信号传导级联中的分子开关。Rho蛋白促进肌动蛋白细胞骨架的重排,并调节细胞形状、附着和迁移。编码的蛋白质有助于将功能性的鸟苷酸交换因子(GEF)复合物从细胞质转移到质膜,在那里激活与ras相关的C3肉毒杆菌毒素底物1,从而促进膜片的形成和细胞迁移。在染色体20和X上已经发现了两个相关的假基因。[RefSeq,2011年8月提供]
Related ID:
NCBI:391
ENSEMBL:ENSG00000177105
HGNC:672
UNIPROT:P84095
OMIM:179505
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
391
2
2
13982 bp
21.31
3
--
3
14
RHOG Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
No data available
Transcripts & Proteins
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
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Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available
Related Drugs
Name
CAS Number
Status
Phase
Link
No data available
References Literature
Title
PMID
Journal
Year
IF
No Data Found!
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