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中文人类
FLG2 - Filaggrin 2
Alias:
IFPS
PSS6
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这个基因编码的类似纤维丝蛋白的蛋白质被钙上调，被钙蛋白酶1降解，并参与上皮内稳态。该编码的蛋白质对皮肤的正常角化是必需的，这个基因的缺陷与皮肤疾病有关。这个蛋白质还具有皮肤屏障保护功能。实际上，除了提供物理屏障外，这个蛋白质的C端片段还具有对抗铜绿假单胞菌和大肠杆菌的抗菌活性。[由RefSeq，2020年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
FLG2 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
