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中文人类
KRT8 - Keratin 8
Alias:
K8
KO
CK8
CK-8
CYK8
K2C8
CARD2
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这个基因是II型角蛋白家族的成员，位于染色体12的长臂上。I型和II型角蛋白异聚物形成中间大小的细胞质中间丝。这个基因的产物通常与角蛋白18二聚化，形成简单单层上皮细胞中的中间丝。这个蛋白在维持细胞结构完整性和信号传导以及细胞分化中发挥作用。这个基因的突变导致隐源性肝硬化。已经发现了这个基因的替代剪接转录变异体。[RefSeq，2012年1月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
KRT8 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
