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中文人类
KRAS - KRAS Proto-oncogene, GTPase
Alias:
NS
NS3
OES
CFC2
RALD
K-Ras
KRAS1
KRAS2
RASK2
KI-RAS
C-K-RAS
K-RAS2A
K-RAS2B
K-RAS4A
K-RAS4B
K-Ras 2
'C-K-RAS
c-Ki-ras
c-Ki-ras2
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这种基因是哺乳动物ras基因家族的Kirsten ras癌基因同源物，编码一个属于小GTP酶超家族的蛋白质。一个氨基酸的替换导致了一种激活突变。产生的转化蛋白与各种恶性肿瘤有关，包括肺腺癌、粘液性腺瘤、胰腺癌和结直肠癌。可选的剪接导致编码两种C端区域不同的异构体的变异。[由RefSeq，2008年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
KRAS Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
