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中文人类
KPNA1 - Karyopherin Subunit Alpha 1
Alias:
RCH2
SRP1
IPOA5
NPI-1
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真核细胞中细胞核和细胞质之间分子的运输是由核孔复合体（NPC）介导的，该复合体由60-100种蛋白质组成。小分子（最大70kD）可以通过非选择性扩散通过核孔，而较大的分子则通过主动过程运输。此基因编码的蛋白质属于导入素α家族，并涉及核蛋白导入。该蛋白质与重组激活基因1（RAG1）蛋白质相互作用，并可能是RAG1泛素连接酶的潜在底物。选择性剪接导致多个转录变异体。[RefSeq，2012年11月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
KPNA1 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
