人类

KCND2 - Potassium Voltage-gated Channel Subfamily D Member 2

Alias:
RK5
KV4.2
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
电压门控钾(Kv)通道在功能和结构上都是最复杂的电压门控离子通道类别。它们的功能包括调节神经递质释放、心率、胰岛素分泌、神经元兴奋性、上皮电解质运输、平滑肌收缩和细胞体积。在果蝇中已经发现了四个与钾通道基因序列相关的基因-shaker、shaw、shab和shal,每个基因都有一个人类同源基因。这个基因编码一个钾离子通道,电压门控,shal相关亚家族成员,它们形成电压激活的A型钾离子通道,在动作电位的复极化阶段中起着重要作用。这个成员调节一种快速失活的A型外向钾电流,它不受N端控制,就像Shaker通道一样。[由RefSeq,2008年7月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
2
6
477430 bp
70.54
298
1
4
29

KCND2 Genetics information (+)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Comparison
Al agent
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