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中文人类
KCNA2 - Potassium Voltage-gated Channel Subfamily A Member 2
Alias:
HK4
MK2
HBK5
NGK1
RBK2
DEE32
HUKIV
KV1.2
EIEE32
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钾通道代表了从功能和结构角度来看最复杂的电压门控离子通道类。它们的功能多样，包括调节神经递质释放、心率、胰岛素分泌、神经元兴奋性、上皮电解质运输、平滑肌收缩和细胞体积。在果蝇中已经发现了四个序列相关的钾通道基因-shaker、shaw、shab和shal，每个基因都有一个人类同源物。这个基因编码一个钾通道、电压门控、shaker相关亚家族的成员。这个成员包含六个跨膜结构域，第四个区段有一个shaker类型的重复。它属于延迟整流器类，该类成员的成员允许神经细胞在动作电位后高效地去极化。这个基因的无内含子编码区位于染色体1上的基因KCNA3和KCNA10附近。[由RefSeq，2008年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
KCNA2 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
