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中文人类
ITGB7 - Integrin Subunit Beta 7
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这个基因编码一个属于整合素超家族的蛋白质。这个家族的成员是粘附受体，负责将细胞外的基质信号传递到细胞。整合素是异源整膜蛋白质，由一个alpha链和一个beta链组成。编码的蛋白质与alpha4链或alphaE链形成二聚体，并在白细胞粘附中发挥作用。与alpha4二聚化形成归巢受体，使淋巴细胞迁移到肠道粘膜和Peyer's斑。与alphaE二聚化允许与配体上皮钙粘蛋白结合，这是一种依赖钙的粘附分子。交替剪接导致多个转录变异体。已描述了该基因的额外交替剪接转录变异体，但其全长性质尚不清楚。[RefSeq，2013年9月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
ITGB7 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
