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中文人类
ITGB2 - Integrin Subunit Beta 2
Alias:
LAD
CD18
MF17
MFI7
LCAMB
LFA-1
MAC-1
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这个基因编码一个整合素β链，它可以与多个不同的α链结合形成不同的整合素异二聚体。整合素是整合在细胞表面的整联蛋白，参与细胞粘附以及细胞表面介导的信号传导。编码的蛋白质在免疫应答中扮演重要角色，而该基因的缺陷导致白细胞粘附缺陷。可变剪接导致多个转录变异体。[由RefSeq，2014年12月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
ITGB2 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
