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中文人类
ITGA5 - Integrin Subunit Alpha 5
Alias:
FNRA
CD49e
VLA-5
VLA5A
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这个基因的产物属于整合素α链家族。整合素是异源二聚体整膜蛋白，由α亚单位和β亚单位组成，负责细胞表面的粘附和信号传导。编码的前原蛋白在蛋白水解过程中被处理，产生组成α5亚单位的光链和重链。这个亚单位与β1亚单位结合，形成纤连蛋白受体。这个整合素可能促进肿瘤侵袭，并且这个基因的高表达可能与肺癌患者的较短生存时间相关。注意，整合素α5和整合素αV亚单位是由不同的基因编码的。[RefSeq，2015年10月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
ITGA5 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
