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中文人类
ITGA2B - Integrin Subunit Alpha 2b
Alias:
GT
GT1
GTA
CD41
GP2B
HPA3
CD41B
GPIIb
BDPLT2
BDPLT16
PPP1R93
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这个基因编码整合素α链家族蛋白质的一员。编码的前原蛋白在蛋白水解过程中被加工成轻链和重链，通过二硫键连接形成α-IIb/β-3整合素细胞粘附受体的亚单位。这个受体在血液凝固系统中扮演着关键角色，通过介导血小板聚集。这个基因的突变与血小板型出血障碍有关，其特点是血小板聚集失败，包括Glanzmann血栓病。[由RefSeq，2016年1月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
ITGA2B Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
