Syne2 - spectrin repeat containing nuclear envelope protein 2

Predicted to enable actin binding activity and cytoskeleton-nuclear membrane anchor activity. Predicted to be involved in several processes, including centrosome localization; nuclear migration; and regulation of cilium assembly. Predicted to act upstream of or within several processes, including fibroblast migration; nuclear envelope organization; and protein localization to nucleus. Predicted to be located in several cellular components, including cell projection membrane; focal adhesion; and nucleus. Predicted to be part of meiotic nuclear membrane microtubule tethering complex. Used to study cryptorchidism. Human ortholog(s) of this gene implicated in autosomal dominant Emery-Dreifuss muscular dystrophy 5. Orthologous to human SYNE2 (spectrin repeat containing nuclear envelope protein 2). [provided by Alliance of Genome Resources, Apr 2022]