Predicted to enable 1-phosphatidylinositol-3-kinase activity and 1-phosphatidylinositol-4-phosphate 3-kinase activity. Involved in negative regulation of gene expression. Predicted to be located in cytosol. Predicted to be part of phosphatidylinositol 3-kinase complex. Predicted to be active in cytoplasm and plasma membrane. Human ortholog(s) of this gene implicated in colorectal cancer; endometrial cancer; and immunodeficiency 14. Orthologous to human PIK3CD (phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta). [provided by Alliance of Genome Resources, Apr 2022]