Bank1 - B-cell scaffold protein with ankyrin repeats 1

Predicted to enable enzyme binding activity; signaling adaptor activity; and signaling receptor binding activity. Predicted to be involved in several processes, including negative regulation of B cell activation; negative regulation of protein kinase B signaling; and positive regulation of peptidyl-tyrosine phosphorylation. Predicted to act upstream of or within negative regulation of gene expression; positive regulation of MAPK cascade; and response to bacterium. Predicted to be located in perinuclear region of cytoplasm. Human ortholog(s) of this gene implicated in autoimmune disease (multiple) and systemic scleroderma (multiple). Orthologous to human BANK1 (B cell scaffold protein with ankyrin repeats 1). [provided by Alliance of Genome Resources, Apr 2022]