大鼠

Selenot - selenoprotein T

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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码一个含硒蛋白,在活性部位含有一个硒半胱氨酸(Sec)残基。Sec是由UGA密码子编码的,通常作为翻译终止信号。硒蛋白mRNA的3'UTR含有保守的茎环结构,即Sec插入序列(SECIS)元素,这是将UGA识别为Sec密码子而非终止信号所必需的。该蛋白定位在内质网中,属于SelWTH家族,具有类似硫氧还蛋白的折叠结构,并在几个氧化还原活性蛋白中发现一个保守的CxxU(C是半胱氨酸,U是Sec)基序。在老鼠的研究中表明,这个基因在调节钙稳态和平滑肌收缩中起作用。这个基因的高诱导也与神经、内分泌和代谢组织中的发生学和再生过程相关。这个位点的假基因已经在染色体4上被鉴定。[RefSeq,2017年8月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
1
6
17052 bp
22.29
5
3

Selenot Genetics information (+)

mRatBN7.2

Sequence Homology

Transcripts & Proteins

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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
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