Edar - ectodysplasin-A receptor

Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in positive regulation of I-kappaB kinase/NF-kappaB signaling and positive regulation of JNK cascade. Predicted to act upstream of or within several processes, including animal organ development; positive regulation of NIK/NF-kappaB signaling; and positive regulation of gene expression. Predicted to be located in apical part of cell. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in ectodermal dysplasia 10A and ectodermal dysplasia 10B. Orthologous to human EDAR (ectodysplasin A receptor). [provided by Alliance of Genome Resources, Apr 2022]