Epg5 - ectopic P-granules 5 autophagy tethering factor

Predicted to be involved in cellular response to dsDNA; endosome to lysosome transport; and nucleotide transport. Predicted to act upstream of with a positive effect on toll-like receptor 9 signaling pathway. Predicted to act upstream of or within autophagosome maturation and endocytic recycling. Predicted to be located in lysosome and perinuclear region of cytoplasm. Human ortholog(s) of this gene implicated in Vici syndrome. Orthologous to human EPG5 (ectopic P-granules autophagy protein 5 homolog). [provided by Alliance of Genome Resources, Apr 2022]