Predicted to enable several functions, including IkappaB kinase activity; K48-linked polyubiquitin modification-dependent protein binding activity; and NF-kappaB-inducing kinase activity. Predicted to be involved in several processes, including interleukin-17-mediated signaling pathway; positive regulation of signal transduction; and regulation of RNA metabolic process. Predicted to be located in PML body and mitochondrial membrane. Predicted to be active in cytoplasm. Orthologous to human IKBKE (inhibitor of nuclear factor kappa B kinase subunit epsilon). [provided by Alliance of Genome Resources, Apr 2022]