Fgd1 - FYVE, RhoGEF and PH domain containing 1

Predicted to enable guanyl-nucleotide exchange factor activity and small GTPase binding activity. Predicted to be involved in several processes, including filopodium assembly; regulation of GTPase activity; and regulation of cell shape. Predicted to act upstream of or within cytoskeleton organization. Predicted to be located in Golgi apparatus; lamellipodium; and ruffle. Human ortholog(s) of this gene implicated in X-linked Aarskog syndrome and non-syndromic X-linked intellectual disability. Orthologous to human FGD1 (FYVE, RhoGEF and PH domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]