Col4a3 - collagen type IV alpha 3 chain

Predicted to enable integrin binding activity. Predicted to be an extracellular matrix structural constituent. Involved in response to glucose. Predicted to be located in endoplasmic reticulum. Predicted to be part of collagen type IV trimer. Predicted to be active in basement membrane and extracellular space. Used to study glomerulonephritis. Human ortholog(s) of this gene implicated in Alport syndrome; autosomal dominant Alport syndrome; autosomal recessive Alport syndrome; benign familial hematuria; and end stage renal disease. Orthologous to human COL4A3 (collagen type IV alpha 3 chain). [provided by Alliance of Genome Resources, Apr 2022]