Traf3 - Tnf receptor-associated factor 3

Predicted to enable enzyme binding activity; identical protein binding activity; and tumor necrosis factor receptor binding activity. Predicted to be involved in several processes, including regulation of gene expression; regulation of intracellular signal transduction; and tumor necrosis factor-mediated signaling pathway. Predicted to be located in cytoplasm. Predicted to be part of CD40 receptor complex. Predicted to be active in cytoplasmic side of plasma membrane. Human ortholog(s) of this gene implicated in brain disease. Orthologous to human TRAF3 (TNF receptor associated factor 3). [provided by Alliance of Genome Resources, Apr 2022]