大鼠

Mthfr - methylenetetrahydrofolate reductase

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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
具有NADP结合活性;黄素腺嘌呤二核苷酸结合活性;和甲基四氢叶酸还原酶(NAD(P)H)活性。参与几个过程,包括同型半胱氨酸代谢过程;对白细胞介素-1的反应;和对维生素的反应。位于细胞质和突触中。作为甲状腺功能亢进症、甲状腺功能减退症和肝脏良性肿瘤的生物标志物。这个基因的人类同源物涉及几种疾病,包括自身免疫性疾病(多种);癌(多种);心血管系统疾病(多种);血液癌症(多种);和肾脏衰竭(多种)。与人类MTHFR(甲基四氢叶酸还原酶)正交。[由基因组资源联盟,2022年4月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
5
12
19752 bp
Unknown
8
2

Mthfr Genetics information (+)

mRatBN7.2

Sequence Homology

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
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