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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
大鼠
Tmub1 - transmembrane and ubiquitin-like domain containing 1
Alias:
Hops
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码的蛋白质属于一组整合性泛素样结构域含有蛋白质,参与多种细胞过程。在鼠中,该蛋白质存在未切割的跨膜形式以及切割后在细胞核和细胞质之间穿梭的形式。在大鼠肝脏再生过程中,已经表明该蛋白质从细胞质向细胞核穿梭以抑制肝细胞增殖。纯合子无效突变小鼠显示正常的发育和生理,但在光:暗周期黑暗阶段表现出强烈的活动增加,表明在行为调控中起作用。可变剪接导致多个转录变异体。[RefSeq,2015年3月提供]
Related ID:
NCBI:362301
UNIPROT:Q53AQ4
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
362301
3
3
2567 bp
26.35
4
6
Tmub1 Genetics information (+)
mRatBN7.2
Sequence Homology
Transcripts & Proteins
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#
Transcript
Length(nt)
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CDS(bp)
Protein
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* This data comes from NCBI.
Gene Expression
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