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中文人类
IDO1 - Indoleamine 2,3-dioxygenase 1
Alias:
IDO
INDO
IDO-1
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这个基因编码吲哚胺2,3-双加氧酶（IDO）——一种催化色胺分解为N-甲酰-L-犬尿氨酸的第一个限速步骤的血红素酶。这种酶作用于多种色氨酸底物，包括D-色氨酸、L-色氨酸、5-羟色氨酸、色胺和血清素。这种酶被认为在各种病理生理过程中发挥作用，如抗菌和抗肿瘤防御、神经病理学、免疫调节和抗氧化活性。通过在树突状细胞、单核细胞和巨噬细胞中表达，这种酶通过细胞周围对必需氨基酸色氨酸的分解代谢来调节T细胞的行为。[RefSeq，2011年2月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
IDO1 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
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Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
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Tile View
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Transcript
Length(nt)
Exon Count
CDS(bp)
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Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
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Abundance
Alphabetical
Cell-specific RNA expression
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Abundance
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Regulation
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MGI
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References Literature
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