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中文人类
IMPDH2 - Inosine Monophosphate Dehydrogenase 2
Alias:
IMPD2
IMPDH-II
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这个基因编码新生鸟苷核苷酸生物合成中的限速酶。因此，它涉及到维持细胞中用于DNA和RNA合成的鸟苷脱氧核糖核苷酸和核糖核苷酸池。编码的蛋白质催化NAD依赖的肌苷-5'-一磷酸氧化成黄嘌呤-5'-一磷酸，然后转化为鸟苷-5'-一磷酸。这个基因在某些肿瘤中上调，表明它可能在恶性转化中发挥作用。[由RefSeq，2008年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
IMPDH2 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
