Gas8 - growth arrest specific 8

Predicted to enable microtubule binding activity and small GTPase binding activity. Predicted to be involved in several processes, including flagellated sperm motility; positive regulation of protein localization to cilium; and positive regulation of smoothened signaling pathway. Predicted to act upstream of or within brain development; determination of left/right symmetry; and epithelial cilium movement involved in extracellular fluid movement. Predicted to be located in several cellular components, including cytoskeleton; cytosol; and sperm flagellum. Predicted to be active in Golgi apparatus and microtubule. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia 33. Orthologous to human GAS8 (growth arrest specific 8). [provided by Alliance of Genome Resources, Apr 2022]