Cbfb - core-binding factor subunit beta

Enables DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II; protein polyubiquitination; and regulation of alpha-beta T cell differentiation. Predicted to act upstream of or within several processes, including hemopoiesis; osteoblast differentiation; and positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of core-binding activity factor complex. Human ortholog(s) of this gene implicated in acute myeloid leukemia. Orthologous to human CBFB (core-binding factor subunit beta). [provided by Alliance of Genome Resources, Apr 2022]