Arap3 - ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3

Predicted to enable GTPase activator activity; phosphatidylinositol-3,4,5-trisphosphate binding activity; and phosphatidylinositol-3,4-bisphosphate binding activity. Predicted to be involved in positive regulation of GTPase activity and signal transduction. Predicted to act upstream of or within negative regulation of Ras protein signal transduction; negative regulation of cell migration; and regulation of cell shape. Predicted to be located in cytoplasm and lamellipodium. Predicted to be active in ruffle. Orthologous to human ARAP3 (ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3). [provided by Alliance of Genome Resources, Apr 2022]