Atxn7 - ataxin 7

Predicted to enable chromatin binding activity. Predicted to be involved in histone deubiquitination; microtubule cytoskeleton organization; and negative regulation of microtubule depolymerization. Predicted to act upstream of or within negative regulation of insulin-like growth factor receptor signaling pathway; negative regulation of phosphorylation; and positive regulation of transcription by RNA polymerase II. Predicted to be located in cytosol; microtubule cytoskeleton; and nucleoplasm. Human ortholog(s) of this gene implicated in spinocerebellar ataxia type 7. Orthologous to human ATXN7 (ataxin 7). [provided by Alliance of Genome Resources, Apr 2022]