Enables L-iduronidase activity and signaling receptor binding activity. Involved in glycosaminoglycan catabolic process. Located in coated vesicle and lysosome. Biomarker of gastric ulcer. Human ortholog(s) of this gene implicated in Scheie syndrome; mucopolysaccharidosis I; mucopolysaccharidosis Ih; and mucopolysaccharidosis Ih/s. Orthologous to human IDUA (alpha-L-iduronidase). [provided by Alliance of Genome Resources, Apr 2022]