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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
大鼠
Brca2 - BRCA2, DNA repair associated
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
激活单链DNA结合活性。参与几个过程,包括在减数分裂有丝分裂I板会议中同源染色体定向;对雌二醇的反应;和精子的发生。预测位于几个细胞组件中,包括中心体;染色体,端粒区;和核腔。预测在细胞核中活性。用于研究睾丸萎缩;癌症;白内障;不育;和骨肉瘤。导管癌和前列腺癌的生物标志物。这个基因的人类同源物涉及几种疾病,包括Fanconi贫血(多种);脑癌(多种);遗传性乳腺癌卵巢癌综合症;黑色素瘤(多种);和生殖器官癌症(多种)。与人类BRCA2(BRCA2 DNA修复相关)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:360254
ENSEMBL:ENSRNOG00000001111
UNIPROT:O35923
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
360254
7
27
44298 bp
Unknown
26
1
Brca2 Genetics information (+)
mRatBN7.2
Sequence Homology
Transcripts & Proteins
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* This data comes from NCBI.
Gene Expression
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