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中文人类
IL15RA - Interleukin 15 Receptor Subunit Alpha
Alias:
CD215
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这个基因编码一种特异性结合白细胞介素15（IL15）的高亲和力细胞因子受体。IL15和IL2的受体共享两个亚基，IL2Rβ和IL2Rγ。这构成了IL15和IL2许多重叠生物活性的基础。这个基因编码的蛋白质在结构上与IL2Rα相关，这是高亲和力结合IL2所需的额外α亚基。与IL2RA不同，IL15RA能够独立于其他亚基与IL15高亲和力结合，这表明IL15和IL2之间具有不同的作用。据报道，这个受体能增强细胞增殖和凋亡抑制剂BCL2L1/BCL2-XL和BCL2的表达。这个基因的多个可变剪接转录变异体已经报道过。[RefSeq，2010年4月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
IL15RA Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
