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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
IL13RA1 - Interleukin 13 Receptor Subunit Alpha 1
Alias:
NR4
CT19
CD213A1
IL-13Ra
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码的蛋白质是白介素13受体的亚单位。这个亚单位与IL4受体的α亚单位形成受体复合物,IL4和IL13受体共享这个亚单位。这个亚单位作为IL13受体的主要IL13结合亚单位,也可能作为IL4受体的成分。这个蛋白质已经显示能够与酪氨酸激酶TYK2结合,从而可能调节由IL13和IL4诱导的JAK1、STAT3和STAT6激活的信号过程。[由RefSeq提供,2008年7月]
Related ID:
NCBI:3597
ENSEMBL:ENSG00000131724
HGNC:5974
UNIPROT:P78552
OMIM:300119
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
3597
2
11
77623 bp
48.76
15
--
11
7
IL13RA1 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
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Transcripts & Proteins
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* This data comes from NCBI.
Gene Expression
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