Home
Toolbox
Resource
Workflow
Tutorials
Citations
Downloads
Mutation Al-Predictor Flow
Gene-to-Mutation Flow
News & Insights
Genetic Encyclopedia
Frontiers
Industry Insights
Case Studies
About Us
About the Site
Contact Us
Private Policy
User Agreement
COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
Log In
|
Sign Up
中文
人类
IL13 - Interleukin 13
Alias:
P600
IL-13
Create a favorites folder
Cancel
Confirm
Add To Favorites
Select a favorites
Description
New favorites >>
Cancel
Confirm
Favorite
Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码一种主要由激活的Th2细胞产生的免疫调节细胞因子。这种细胞因子涉及B细胞成熟和分化的几个阶段。它上调CD23和MHC II类分子的表达,并促进B细胞的IgE类型转换。这种细胞因子下调巨噬细胞活性,从而抑制促炎细胞因子和趋化因子的产生。这种细胞因子被发现对于过敏原诱导的哮喘的发病机制是至关重要的,但其作用是通过与IgE和嗜酸性粒细胞无关的机制进行的。这个基因,IL3、IL5、IL4和CSF2在染色体5q上形成一个细胞因子基因簇,这个基因特别靠近IL4。[由RefSeq,2008年7月提供]
Related ID:
NCBI:3596
ENSEMBL:ENSG00000169194
HGNC:5973
UNIPROT:P35225
OMIM:147683
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
3596
4
4
4589 bp
15.79
6
2
15
17
IL13 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
No data available
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Reset
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available
Related Drugs
Name
CAS Number
Status
Phase
Link
No data available
References Literature
Title
PMID
Journal
Year
IF
No Data Found!
Wechat
Mutation Direct
Sequence
Comparison
Al agent
Tutorials
Back to top