人类

IL13 - Interleukin 13

Alias:
P600
IL-13
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码一种主要由激活的Th2细胞产生的免疫调节细胞因子。这种细胞因子涉及B细胞成熟和分化的几个阶段。它上调CD23和MHC II类分子的表达,并促进B细胞的IgE类型转换。这种细胞因子下调巨噬细胞活性,从而抑制促炎细胞因子和趋化因子的产生。这种细胞因子被发现对于过敏原诱导的哮喘的发病机制是至关重要的,但其作用是通过与IgE和嗜酸性粒细胞无关的机制进行的。这个基因,IL3、IL5、IL4和CSF2在染色体5q上形成一个细胞因子基因簇,这个基因特别靠近IL4。[由RefSeq,2008年7月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
4
4
4589 bp
15.79
6
2
15
17

IL13 Genetics information (+)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Comparison
Al agent
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