Home
Toolbox
Resource
Workflow
Tutorials
Citations
Downloads
Mutation Al-Predictor Flow
Gene-to-Mutation Flow
News & Insights
Genetic Encyclopedia
Frontiers
Industry Insights
Case Studies
About Us
About the Site
Contact Us
Private Policy
User Agreement
COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
Log In
|
Sign Up
中文
人类
IL10RA - Interleukin 10 Receptor Subunit Alpha
Alias:
CD210
IL10R
CD210a
CDW210A
HIL-10R
IL-10R1
Create a favorites folder
Cancel
Confirm
Add To Favorites
Select a favorites
Description
New favorites >>
Cancel
Confirm
Favorite
Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码的蛋白质是白介素10的受体。这个蛋白质在结构上与干扰素受体有关。已经证明它可以传递白介素10的免疫抑制信号,从而抑制促炎细胞因子的合成。这个受体已被报道可以通过胰岛素受体底物-2/PI 3-激酶/AKT途径促进前髓细胞祖细胞的生存。这个受体的激活导致JAK1和TYK2激酶的酪氨酸磷酸化。已经发现这个基因有两个转录变异体,一个编码蛋白质,另一个不编码蛋白质。[由RefSeq,2009年1月提供]
Related ID:
NCBI:3587
ENSEMBL:ENSG00000110324
HGNC:5964
UNIPROT:Q13651
OMIM:146933
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
3587
4
7
16644 bp
63.00
369
3
13
15
IL10RA Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
No data available
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Reset
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available
Related Drugs
Name
CAS Number
Status
Phase
Link
No data available
References Literature
Title
PMID
Journal
Year
IF
No Data Found!
Wechat
Mutation Direct
Sequence
Comparison
Al agent
Tutorials
Back to top