人类

IL10RA - Interleukin 10 Receptor Subunit Alpha

Alias:
CD210
IL10R
CD210a
CDW210A
HIL-10R
IL-10R1
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码的蛋白质是白介素10的受体。这个蛋白质在结构上与干扰素受体有关。已经证明它可以传递白介素10的免疫抑制信号,从而抑制促炎细胞因子的合成。这个受体已被报道可以通过胰岛素受体底物-2/PI 3-激酶/AKT途径促进前髓细胞祖细胞的生存。这个受体的激活导致JAK1和TYK2激酶的酪氨酸磷酸化。已经发现这个基因有两个转录变异体,一个编码蛋白质,另一个不编码蛋白质。[由RefSeq,2009年1月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
4
7
16644 bp
63.00
369
3
13
15

IL10RA Genetics information (+)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Comparison
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