人类

IL7R - Interleukin 7 Receptor

Alias:
ILRA
CD127
IL7RA
CDW127
IMD104
sIL-7R
lnc-IL7R
IL7Ralpha
IL-7Ralpha
IL-7R-alpha
Favorite
Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码的蛋白质是白介素7(IL7)的受体。这个受体功能需要白介素2受体,γ链(IL2RG),这是一个各种细胞因子受体,包括白介素2、4、7、9和15共用的常见γ链。这个蛋白质在淋巴细胞发育过程中的V(D)J重组中扮演关键角色。这个基因的缺陷可能与严重联合免疫缺陷(SCID)有关。已经发现了可替代剪接的转录变异体。[由RefSeq,2015年12月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
4
8
22713 bp
51.58
396
4
11
9

IL7R Genetics information (+)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
Wechat
Mutation Direct
Sequence
Comparison
Al agent
Tutorials
Back to top