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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
IL7R - Interleukin 7 Receptor
Alias:
ILRA
CD127
IL7RA
CDW127
IMD104
sIL-7R
lnc-IL7R
IL7Ralpha
IL-7Ralpha
IL-7R-alpha
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码的蛋白质是白介素7(IL7)的受体。这个受体功能需要白介素2受体,γ链(IL2RG),这是一个各种细胞因子受体,包括白介素2、4、7、9和15共用的常见γ链。这个蛋白质在淋巴细胞发育过程中的V(D)J重组中扮演关键角色。这个基因的缺陷可能与严重联合免疫缺陷(SCID)有关。已经发现了可替代剪接的转录变异体。[由RefSeq,2015年12月提供]
Related ID:
NCBI:3575
ENSEMBL:ENSG00000168685
HGNC:6024
UNIPROT:P16871
OMIM:146661
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
3575
4
8
22713 bp
51.58
396
4
11
9
IL7R Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
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Transcripts & Proteins
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* This data comes from NCBI.
Gene Expression
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No Data Found!
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